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Introduction

The FAMILY consortium aims to deepen our understanding of the intergenerational transmission of
mental illness, with focus on mood and psychotic disorders. For this purpose, FAMILY is set to explore
the mechanisms of intergenerational transmission of psychiatric disorders, from the genetic,
epigenetic, environmental and neuroimaging perspectives, and build novel prediction models that
encompass the familial context. Hence, FAMILY will gather the largest population and high-risk
offspring cohorts along with animal models and will implement state-of-the art approaches to
integrate and analyze the data. Moreover, the consortium will investigate the bioethical and social
issues brought by risk prediction. Ultimately, the FAMILY consortium will help unravel the target of
preventive strategies to stop the intergenerational transmission of mood and psychotic disorders by
the identification of susceptibility and resilience markers.

Due to its interdisciplinary and translational nature, the FAMILY consortium will employ and generate
large quantities of multimodal human data, which is subjected to strict ethical regulations and must
be handled in conformity with Standard Operating Procedures (SOPs).
The purpose of this data management plan is to establish a framework that adheres to the strictest
data protection standards while guaranteeing data findability, accessibility, interoperability and
reuse.

Definitions, Abbreviations and Acronyms

Abbreviation/AcronymDEFINITION
DREDigital research environment
SOPsStandard operating procedures
DTAData Transfer Agreement
NANot available
Table 1 List of Abbreviations and Acronyms